Gene information
Official symbol TWIST1
Official full name twist family bHLH transcription factor 1
Gene type protein-coding gene
Chromosome7p21.1
Alias symbolSCS; H-twist; BPES2; bHLHa38; CRS1
Previous symbolACS3; BPES3; TWIST; CRS
Gene familyBasic helix-loop-helix proteins
Resources
Entrez Gene 7291
HGNC HGNC:12428
Ensembl ENSG00000122691
Vega OTTHUMG00000090821
UCSC uc003sum.3
GO terms: 151 records
GO Description Category LogP Number of genes Detail
GO:0001221 transcription coregulator binding GO Molecular Functions -4.88806294 16 More
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0001649 osteoblast differentiation GO Biological Processes -6.81659337 21 More
GO:0001654 eye development GO Biological Processes -3.29977134 15 More
GO:0001666 response to hypoxia GO Biological Processes -40.6131384 77 More
GO:0001667 ameboidal-type cell migration GO Biological Processes -17.0771232 40 More
GO:0001701 in utero embryonic development GO Biological Processes -8.76987260 44 More
GO:0001755 neural crest cell migration GO Biological Processes -8.06132628 15 More
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001838 embryonic epithelial tube formation GO Biological Processes -6.74209917 20 More
GO:0001841 neural tube formation GO Biological Processes -5.20987525 16 More
GO:0001843 neural tube closure GO Biological Processes -4.06290305 13 More
GO:0001933 negative regulation of protein phosphorylation GO Biological Processes -19.8214973 59 More
GO:0002009 morphogenesis of an epithelium GO Biological Processes -21.4354199 71 More
GO:0003007 heart morphogenesis GO Biological Processes -18.8519524 49 More
GO:0003151 outflow tract morphogenesis GO Biological Processes -7.88412825 17 More
GO:0003170 heart valve development GO Biological Processes -11.9253160 20 More
GO:0003176 aortic valve development GO Biological Processes -8.77845673 13 More
GO:0003179 heart valve morphogenesis GO Biological Processes -9.26383069 16 More
GO:0003180 aortic valve morphogenesis GO Biological Processes -6.3383802 10 More
GO:0003197 endocardial cushion development GO Biological Processes -7.47578775 13 More
GO:0003203 endocardial cushion morphogenesis GO Biological Processes -4.87335450 9 More
GO:0007423 sensory organ development GO Biological Processes -8.10586983 29 More
GO:0007507 heart development GO Biological Processes -29.3002557 91 More
GO:0007517 muscle organ development GO Biological Processes -15.8908392 49 More
GO:0008134 transcription factor binding GO Molecular Functions -5.50998540 50 More
GO:0008283 cell population proliferation GO Biological Processes -17.2298624 68 More
GO:0009792 embryo development ending in birth or egg hatching GO Biological Processes -12.9988944 72 More
GO:0009896 positive regulation of catabolic process GO Biological Processes -13.5088608 63 More
GO:0010563 negative regulation of phosphorus metabolic process GO Biological Processes -21.7837721 71 More
GO:0010565 regulation of cellular ketone metabolic process GO Biological Processes -15.3155739 32 More
GO:0010717 regulation of epithelial to mesenchymal transition GO Biological Processes -12.1292389 25 More
GO:0010718 positive regulation of epithelial to mesenchymal transition GO Biological Processes -11.466629 18 More
GO:0014020 primary neural tube formation GO Biological Processes -5.01152693 15 More
GO:0014032 neural crest cell development GO Biological Processes -11.9399165 15 More
GO:0014033 neural crest cell differentiation GO Biological Processes -12.2997127 24 More
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling GO Biological Processes -15.9250248 30 More
GO:0016331 morphogenesis of embryonic epithelium GO Biological Processes -7.49308957 23 More
GO:0019904 protein domain specific binding GO Molecular Functions -3.48133193 23 More
GO:0021915 neural tube development GO Biological Processes -7.57225811 24 More
GO:0022898 regulation of transmembrane transporter activity GO Biological Processes -11.1988499 41 More
GO:0030278 regulation of ossification GO Biological Processes -11.2759455 26 More
GO:0030326 embryonic limb morphogenesis GO Biological Processes -4.09609747 9 More
GO:0031400 negative regulation of protein modification process GO Biological Processes -17.0986645 70 More
GO:0031998 regulation of fatty acid beta-oxidation GO Biological Processes -2.92503639 5 More
GO:0032409 regulation of transporter activity GO Biological Processes -16.9480646 53 More
GO:0032642 regulation of chemokine production GO Biological Processes -25.2850711 37 More
GO:0032675 regulation of interleukin-6 production GO Biological Processes -28.2553997 51 More
GO:0032680 regulation of tumor necrosis factor production GO Biological Processes -32.0729913 56 More
GO:0032720 negative regulation of tumor necrosis factor production GO Biological Processes -18.6356508 28 More
GO:0032755 positive regulation of interleukin-6 production GO Biological Processes -18.6559032 31 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034763 negative regulation of transmembrane transport GO Biological Processes -22.14661 42 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0035051 cardiocyte differentiation GO Biological Processes -18.7205561 33 More
GO:0035107 appendage morphogenesis GO Biological Processes -3.51424431 9 More
GO:0035108 limb morphogenesis GO Biological Processes -3.51424431 9 More
GO:0035113 embryonic appendage morphogenesis GO Biological Processes -4.09609747 9 More
GO:0035115 embryonic forelimb morphogenesis GO Biological Processes -4.03854853 5 More
GO:0035116 embryonic hindlimb morphogenesis GO Biological Processes -3.03394175 6 More
GO:0035136 forelimb morphogenesis GO Biological Processes -3.60556236 5 More
GO:0035137 hindlimb morphogenesis GO Biological Processes -2.50832748 6 More
GO:0035148 tube formation GO Biological Processes -7.32029616 23 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway GO Biological Processes -4.70690316 6 More
GO:0036293 response to decreased oxygen levels GO Biological Processes -40.9544531 79 More
GO:0036294 cellular response to decreased oxygen levels GO Biological Processes -14.5279047 32 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042326 negative regulation of phosphorylation GO Biological Processes -20.6187298 64 More
GO:0042476 odontogenesis GO Biological Processes -9.69427751 24 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0043009 chordate embryonic development GO Biological Processes -11.8113315 68 More
GO:0043010 camera-type eye development GO Biological Processes -3.41918860 14 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043271 negative regulation of ion transport GO Biological Processes -19.3914052 40 More
GO:0043388 positive regulation of DNA binding GO Biological Processes -12.0675836 19 More
GO:0043433 negative regulation of DNA-binding transcription factor activity GO Biological Processes -10.6964949 32 More
GO:0043583 ear development GO Biological Processes -6.67517572 16 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045667 regulation of osteoblast differentiation GO Biological Processes -10.7517956 27 More
GO:0045668 negative regulation of osteoblast differentiation GO Biological Processes -3.60984508 9 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0045766 positive regulation of angiogenesis GO Biological Processes -39.3444092 63 More
GO:0045936 negative regulation of phosphate metabolic process GO Biological Processes -21.8424865 71 More
GO:0046320 regulation of fatty acid oxidation GO Biological Processes -3.51698265 7 More
GO:0048511 rhythmic process GO Biological Processes -10.3377021 38 More
GO:0048562 embryonic organ morphogenesis GO Biological Processes -8.59880895 37 More
GO:0048568 embryonic organ development GO Biological Processes -17.1204114 64 More
GO:0048592 eye morphogenesis GO Biological Processes -1.58766487 12 More
GO:0048593 camera-type eye morphogenesis GO Biological Processes -1.85747522 11 More
GO:0048598 embryonic morphogenesis GO Biological Processes -22.1253699 83 More
GO:0048705 skeletal system morphogenesis GO Biological Processes -7.04838258 29 More
GO:0048706 embryonic skeletal system development GO Biological Processes -2.56739645 13 More
GO:0048729 tissue morphogenesis GO Biological Processes -31.7796969 96 More
GO:0048736 appendage development GO Biological Processes -3.44031493 10 More
GO:0048762 mesenchymal cell differentiation GO Biological Processes -16.1250183 37 More
GO:0048863 stem cell differentiation GO Biological Processes -16.2106470 36 More
GO:0048864 stem cell development GO Biological Processes -12.7283120 16 More
GO:0048880 sensory system development GO Biological Processes -3.47450215 31 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050679 positive regulation of epithelial cell proliferation GO Biological Processes -31.4834672 59 More
GO:0050996 positive regulation of lipid catabolic process GO Biological Processes -5.87603013 9 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051052 regulation of DNA metabolic process GO Biological Processes -4.01973325 42 More
GO:0051090 regulation of DNA-binding transcription factor activity GO Biological Processes -25.8933515 78 More
GO:0051099 positive regulation of binding GO Biological Processes -11.1715489 31 More
GO:0051101 regulation of DNA binding GO Biological Processes -9.69427751 24 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0060021 roof of mouth development GO Biological Processes -2.59996800 6 More
GO:0060173 limb development GO Biological Processes -3.44031493 10 More
GO:0060348 bone development GO Biological Processes -12.2474877 36 More
GO:0060349 bone morphogenesis GO Biological Processes -6.25068095 17 More
GO:0060485 mesenchyme development GO Biological Processes -18.0238 46 More
GO:0060562 epithelial tube morphogenesis GO Biological Processes -17.7630248 53 More
GO:0060606 tube closure GO Biological Processes -4.01197458 13 More
GO:0060973 cell migration involved in heart development GO Biological Processes -7.86308931 9 More
GO:0061061 muscle structure development GO Biological Processes -23.2569142 77 More
GO:0061307 cardiac neural crest cell differentiation involved in heart development GO Biological Processes -5.39331932 6 More
GO:0061308 cardiac neural crest cell development involved in heart development GO Biological Processes -5.39331932 6 More
GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis GO Biological Processes -6.38728364 6 More
GO:0062012 regulation of small molecule metabolic process GO Biological Processes -26.8746473 69 More
GO:0062013 positive regulation of small molecule metabolic process GO Biological Processes -17.9792910 37 More
GO:0070167 regulation of biomineral tissue development GO Biological Processes -10.3239090 23 More
GO:0070482 response to oxygen levels GO Biological Processes -40.7566635 82 More
GO:0070848 response to growth factor GO Biological Processes -40.6139195 102 More
GO:0070888 E-box binding GO Molecular Functions -5.33490415 11 More
GO:0071363 cellular response to growth factor stimulus GO Biological Processes -39.8883675 98 More
GO:0071453 cellular response to oxygen levels GO Biological Processes -14.8173809 34 More
GO:0071456 cellular response to hypoxia GO Biological Processes -14.4449186 31 More
GO:0071639 positive regulation of monocyte chemotactic protein-1 production GO Biological Processes -3.56180292 5 More
GO:0072132 mesenchyme morphogenesis GO Biological Processes -6.89052200 13 More
GO:0072175 epithelial tube formation GO Biological Processes -6.28242122 20 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0090497 mesenchymal cell migration GO Biological Processes -8.76593708 16 More
GO:0090596 sensory organ morphogenesis GO Biological Processes -4.94155170 15 More
GO:0110149 regulation of biomineralization GO Biological Processes -10.9748263 24 More
GO:0140297 DNA-binding transcription factor binding GO Molecular Functions -6.94737226 46 More
GO:0150063 visual system development GO Biological Processes -3.59465978 31 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1901796 regulation of signal transduction by p53 class mediator GO Biological Processes -2.39461048 11 More
GO:1901861 regulation of muscle tissue development GO Biological Processes -2.53742702 7 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -32.3948799 57 More
GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -18.2876323 28 More
GO:1904018 positive regulation of vasculature development GO Biological Processes -39.3444092 63 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:1904888 cranial skeletal system development GO Biological Processes -2.01258862 8 More
GO:1905314 semi-lunar valve development GO Biological Processes -10.3278393 15 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000679 positive regulation of transcription regulatory region DNA binding GO Biological Processes -4.37707433 7 More
GO:2000772 regulation of cellular senescence GO Biological Processes -3.74766542 9 More
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
cg10126205 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
cg14391419 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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